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서울대학교  의학박사

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- 서울대학교 의과대학 삼성암연구소 (연구원)
- 서울대학교 의과대학 약리학교실 (박사후 연구원[POST-DOC])
- Department of Cell Biology & Cancer Biology, Havard Medical School and Dana-Farber Canaer Institute (박사후연구원[POST-DOC])

bullet  주요논문

- 암발생의 분자기전 규명 및 신규 항암제 개발, 줄기세포 분화 조절 전사인자 발굴 - Lim JH. (2014) Zinc finger and BTB domain-containing protein 3 is essential for the growth of cancer cells. BMB Reports - Yoonjin Lee , John Dominy Jr. , Yoon Choi , Michael Jurczak , Nicola Tolliday , Joao Camporez , Helen Chim , Ji-Hong Lim , Hai-Bin Ruan , Xiaoyong Yang , Francisca Vazquez , Piotr Sicinski , Gerald Shulman, and Pere Puigserver. (2014) Cyclin D1-CDK4 Controls Glucose Metabolism Independently of Cell Cycle Progression. Nature - Lim JH, Chi L, Vazquez F, Puigserver P. (2014) Targeting mitochondrial oxidative metabolism in melanomas causes metabolic compensation through glucose and glutamine utilization. Cancer Research - Vazquez F*, Lim JH*, Chim H, Bhalla K, Girnun G, Pierce K, Clish CB, Granter SR, Widlund HR, Spiegelman BM, Puigserver P. (2013) PGC1alpha Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress. Cancer Cell 23 (3):287-301 *Co-first author but listed second. - Lim JH, Gerhart-Hines Z, Dominy JE Jr, Lee Y, Kim S, Tabata M, Xiang Y, Puigserver P. (2013) Oleic Acid Stimulates Complete Oxidation of Fatty Acids Through PKA-Dependent Activation of SIRT1/PGC1alpha Complex. J Biol Chem 288(10):7117-26 - Lim JH, Choi YJ, Cho CH, Park JW. (2012) Protein arginine methyltransferase 5 is an essential component of the hypoxia-inducible factor 1 signaling pathway. Biochem Biophys Res Commun 418(2):254-9 - Gerhart-Hines Z, Dominy JE Jr, Blatter SM, Jedrychowski, M, Banks AS, Lim JH, Chim H, Gygi SP, Puigserver P. (2012) The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+. Molecular Cell 44(6):851-63 - Yoon H, Lim JH, Cho CH, Huang LE, Park JW. (2011) CITED2 controls the hypoxic signaling by snatching p300 from the two distinct activation domains of HIF-1alpha. Biochim Biophys Acta 1813(12):2008-16
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